Why are the ingredients in MenoMulti formulated at these specific amounts?Updated 2 hours ago

MenoMulti was intentionally formulated with the specific amounts below:

Thiamin (Thiamine HCl) – 2 mg

• RDA for adult women is ~1.1 mg.

• 2 mg ≈ ~180% of RDA → gentle but meaningful “top-up.”

• Role:

  • Coenzyme in carbohydrate metabolism and energy production.

  • Supports nervous system function.

Why it makes sense here:
Thiamin sits upstream in energy metabolism. In our formula with CoQ10 + active Bs, a modest bump in thiamin supports the overall “carb → ATP” purpose.

Riboflavin (Riboflavin-5-phosphate) – 1.7 mg

• RDA ~1.1 mg; 1.7 mg ≈ ~150% of RDA.

• Riboflavin-5-phosphate is the coenzyme form (FMN), directly tied to FAD/FMN-dependent reactions.

• Role:

  • Critical for mitochondrial energy metabolism (FAD, FMN).

  • Supports antioxidant enzyme systems (e.g., glutathione pathways).

Why it’s nice here:
We are not just giving more B2; we are giving it in a form that plugs directly into mitochondrial and antioxidant systems, highly aligned with CoQ10 and cellular energy + resilience.

Niacin (Niacinamide) – 1.5 mg NE

• RDA for women ~14 mg NE, so this is a small supportive amount, not a high-dose niacin formula.

• Niacinamide:

  • Converts to NAD⁺/NADP⁺ without causing flushing.

  • Still participates in redox and energy metabolism.

Why we include it:
MenoMulti isn’t trying to be the main niacin source. It provides a small, non-flushing contribution to the NAD⁺ pool that synergizes with CoQ10 and the rest of the B-complex vitamins, without entering “high-dose niacin” territory.

Vitamin B6 (Pyridoxal-5-Phosphate) – 16 mg

• RDA ~1.3–1.5 mg → 16 mg is a purposeful, elevated dose (well below the 100 mg UL).

• P-5-P is the active coenzyme form.

• Role:

  • Cofactor in neurotransmitter synthesis (serotonin, GABA, dopamine).

  • Involved in glycogen breakdown and energy metabolism.

  • Vitamin B6, in its active form, helps your body process homocysteine, an amino acid formed when you break down protein, and works with folate and B12 to keep that system running smoothly.

Why this amount & form:

• Using P-5-P bypasses the need for liver activation of B6.

• 16 mg ensures saturation of key B6-dependent pathways without creeping into neurotoxicity ranges.

• In midlife, where mood, energy, and homocysteine are big themes, this is active B6 at a meaningful dose.

Folate (from L-5-MTHF) – 1700 mcg DFE

• RDA is 400 mcg DFE; this is ~4× RDA.

• L-5-MTHF is the methylated, active form, no need to convert folic acid.

• Role:

  • Central in methylation and homocysteine metabolism (see info above).

  • DNA synthesis & repair; cell division.

  • Works with B12 and B6 in one-carbon metabolism.

Why this is powerful:

• Many midlife women have, or have heard of, MTHFR and want methylfolate, not folic acid.

• L-5-MTHF at this level supports robust methylation capacity (especially in those with genetic or metabolic limitations).

• High enough to “matter,” but not as a treatment dose.

Why we use it:

We chose a clinically meaningful dose of methylfolate, instead of sprinkling in a token amount of folic acid.

Vitamin B12 (Methylcobalamin) – 10 mcg

• RDA is 2.4 mcg → this amount at 10 mcg supports

  • Back up to what food offers

  • Energy and nervous system health in midlife

It’s still a reasonable, everyday dose, not an extreme “mega-dose.”

Some people may not absorb B12 as well from food as they get older, so having a bit more than the bare minimum can be helpful.

• Methylcobalamin:

  • Active methyl form used in methylation reactions.

  • Partners with L-5-MTHF and B6 for homocysteine conversion (see above).

  • Supports nervous system and red blood cell function.

  • Helps the body convert food into energy.

Why we use this:

• B12 is water-soluble; excess is generally excreted in most people.

• Higher B12 doses are commonly used in supplements to ensure adequate absorption; many midlife individuals experience a decline in B12 absorption.

Uses methylcobalamin, the active form of B12, at a meaningful dose to support energy metabolism and homocysteine balance.

MenoMulti includes B12 in a methyl form the body can use right away. The 10 micrograms in each capsule provide more than the bare minimum to support daily energy, red blood cell health, and nervous system function, especially helpful in midlife when B12 can be harder to get and use from food alone.

Biotin – 5000 mcg

• Adequate Intake is ~30 mcg → 5000 mcg 

• Role:

  • Coenzyme in carboxylase enzymes for fatty acid, amino acid, and glucose metabolism.

  • Supports healthy hair, skin, and nails.

This dose:

• Strongly supports our hair/skin/nails.

• Also supports energy metabolism (biotin is a metabolic vitamin, not just used for cosmetic purposes).

Pantothenic Acid (d-Calcium Pantothenate) – 1.7 mg

• Adequate Intake is ~5 mg/day → we are offering a supportive but modest amount.

• Role:

  • Precursor to Coenzyme A (CoA), central to fatty acid oxidation and energy metabolism.

Why it makes sense:

• Most diets provide pantothenic acid fairly well; we are not trying to be the primary source.

• This amount ensures CoA-related pathways aren’t a bottleneck in energy production while keeping the formula focused.